Anti-aging material Let’s extend the healthy life expectancy SIRTMAX (Black Turmeric Extract)

Features of SIRTMAX®

About Black Turmeric…

Black turmeric(Kaempferia parviflora), a plant that belongs to Kaempferia genus of Zingiberaceae (ginger) family, is indigenous to Thailand & Laos. At the location, it has been used as a folk medicine since ancient days, and its characteristic compounds are polymethoxyflavonoids. As for its efficacy, anti-oxidant action, vasodilator action and antiallergic action thus has been used as a folk remedy for nutritional enhancement, sexual vigor enhancement, physical recovery, circulatory system improvement and digestive system improvement.

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About Black Turmeric…

About the labeling system on food functions and nutrients

As a part of the whole nation’s initiative for disease prevention and health care aiming at realizing a society that “extends the healthy life expectancy of the Japanese people”, “the labeling system on food functions and nutrients” was established in April 2015. This system allows manufacturers to show consumers, in an easy-to-understand way, about the health functions of food.
To be authorized as a functional food that conforms to the labeling system on food functions and nutrients food, it is required to submit to the Consumer Affairs Agency (CAA) a “scientific base mandated to describe function of the foods on its label”. This means any company that wants to apply to the system, needs to review literature on the functionality of necessary ingredients as well as verify that its product contains an effective dose of the identified ingredients.
Tokiwa Phytochemical Co., Ltd. offers materials corresponding to the labeling system on food functions and nutrients: VENETRON®(Sleep quality improvement), BILBERON®(Dry eyes, focus accommodative function, eye fatigue), SIRTMAX®(Anti-hyperglycemia, anti-aging), GINKGOLON(Cognitive function improvement).

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Specification of Components

Black turmeric contains an abundance of polymethoxyflavonoids (PMFs). Our SIRTMAX®, contains five kinds of Poly Methoxy Flavonoid from Kaempferia parviflora (KPMF), namely KPMF-2, 3, 5, 8, and 10, more than 15% in total.

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See more details about the raw materials

Link to the page offering information, such as research reports, about plants to be used as raw materials.
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Patent and Authentication

SIRTMAX®applied International Patent Application, acquired trademark sign and obtained the certificate of JIHFS GMP for Health Foods.

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Sum of Five polymethoxyflavonoids (KPMFs), active ingredients ≧15%

Recommended dosage



Tests on humans Carbohydrate metabolism improvement, inhibition of weight gain, inhibition of abdominal girth accumulation, decrease of advanced glycation end products (AGEs) and vascular age of those who have relatively high blood glucose level.
Animal tests Insulin resistance improvement, inhabitation of visceral fat accumulation, inhibition of weight gain.


Acute toxicity (Mouse, bisexual) : > LD502000mg/kg
Ames test: Negative
Safety if confirmed through testing on humans at 7-week intakes (1000mg/day)


Stable for two years in normal temperatures.
98% of active ingredients remained after 6-months being stored at 40℃, 75% humidity.

Wide variety of product forms

A water-soluble type has been newly developed, and can be used for tablets, capsules and drinks.
※ Specification: Polymethoxyflavonoids> 5%

Reference materials

  • a) Natural Product Communications, 9, 1291-1294. (2014)
  • b) Horikawa T, et al., Biol Pharm Bull. 35, (5):686-92. (2012)
  • c) Akase T, et al., J Nat Med. 65, 73-80. (2011)
  • d) Simada T, et al., Fitoterapia. 82, 1272-8. (2011)
  • e) Shimada N, et al., Jpn Pharmacol Ther. 43, (7):997-1005 (2015)

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  • Research Results

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Product PDF

For more Information,call +81-3-5200-1251